Principal Scientist - Medicinal Chemistry
      (nr ref. 2022.06.0005)

      Location: Basel, Switzerland or Wroclaw, Poland


      We are looking for an experienced medicinal chemist to lead all the aspects of medicinal chemistry with special emphasis Hit-to-Lead and Lead Optimization campaigns in the area of Targeted Protein Degradation. The candidates should display great leadership and interpersonal skills to support drug discovery projects in an interdisciplinary setting.


      Duties and responsibilities:

      • Active contribution to project development
      • Data analysis in the areas of FBLG, SBDD, DMPK, and molecular modelling
      • Close support of medicinal chemists (both internal and outsourced), cancer biologist, and biophysicist
      • Reporting results to SVP Chemistry and CSO
      • Mentoring junior personnel in the areas of medicinal chemistry
      • Effective communication with CROs and consultants
      • Management of a small team of researchers executing the project
      • Literature search and analysis in the area of project interest including patent writing and analysis


      • Ph.D. in medicinal or organic chemistry
      • Minimum of 5 years of industry experience (post-PhD/postdoc)
      • Proven track record of Hit-2-Lead and Lead Optimization
      • Proven track record in interdisciplinary project management
      • Knowledge of patent writing and analysis
      • Expert knowledge in SBDD and FBDD methods
      • Knowledge of computational methods and workflow automation is considered as a benefit
      • Ability to travel once a month to Wroclaw site in Poland
      • Very good command of English
      • Experience in people management

      We offer:

      • Full-time employment in a quickly growing biotechnological enterprise
      • Competitive salary
      • Employee stock option plan
      • Opportunities for a constant professional development
      • External training, conferences, workshops
      • Friendly work environment

      We retain the right to contact only selected candidates.

      Please attach this clause to your CV:

      I understand that by sending my application I will consent to the processing of personal data contained therein, including data other than contact or education; professional qualifications and the course of previous employment.


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